KDM4C/GASC1/JMJD2C Polyclonal Antibody


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Cat.No.:  EAb-2559
Product Name:  KDM4C/GASC1/JMJD2C Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect KDM4C/GASC1/JMJD2C
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to a region within the internal sequence amino acids 755-804 of Human KDM4C/ GASC1/ JMJD2C.
Immunogen Sequence:  CLCNLRGGAL KQTKNNKWAH VMCAVAVPEV RFTNVPERTQ IDVGRIPLQR
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, PBS, 2% Sucrose
Applications:  IHC-P, WB
Species Reactivity:  Mouse, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  NP_055876
Alternative Name:  bA146B14.1 antibody/GASC 1 protein antibody/GASC-1 protein antibody
Scientific Background:  Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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