HDAC5 (phospho S498) Polyclonal Antibody


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Cat.No.:  EAb-2560
Product Name:  HDAC5 (phospho S498) Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect HDAC5 (phospho S498)
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human HDAC5 (phospho S498). Immunogen range: 464-513
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.40; 0.02% Sodium azide, PBS, 50% Glycerol, 0.87% Sodium chloride
Applications:  WB, IHC-P, ELISA
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9UQL6
Alternative Name:  Antigen NY CO 9 antibody/Antigen NY-CO-9 antibody/HD5 antibody
Scientific Background:  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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