HDAC2 Polyclonal Antibody (C-terminal)


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Cat.No.:  EAb-2569
Product Name:  HDAC2 Polyclonal Antibody (C-terminal)
Product Overview:  Rabbit polyclonal to detect HDAC2 - C-terminal
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide within Human HDAC2 (C terminal). (Carrier-protein conjugated).
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.00; 0.01% Thimerosal (merthiolate), 1.21% Tris, 0.75% Glycine, 20% Glycerol
Applications:  ChIP, IHC-P, WB, ICC/IF, IP
Species Reactivity:  Mouse, Rat, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q92769
Alternative Name:  D10Wsu179e antibody/HD 2 antibody/HD2 antibody
Scientific Background:  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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