| Cat.No.: | EAb-2579 |
| Product Name: | HDAC7 Monoclonal Antibody (HDAC7-97) |
| Product Overview: | Mouse monoclonal (HDAC7-97) to detect HDAC7 |
| Antibody Type: | Monoclonal |
| Clone Designation: | HDAC7-97 |
| Immunogen: | Synthetic peptide conjugated to KLH, corresponding to amino acids 137-155 of Mouse HDAC7 |
| Immunogen Sequence: | YRTLEPLDTEGAARSVLSS |
| Host: | Mouse |
| Isotype: | IgG1 |
| Appearance: | Liquid |
| Formulation: | pH: 7.40; 0.097% Sodium azide, 0.0268% PBS |
| Applications: | ELISA, IP, ICC, WB, ChIP |
| Species Reactivity: | Mouse, Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | DKFZP586J0917 antibody/FLJ99588 antibody/HD 7a antibody |
| Scientific Background: | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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