HDAC4 Monoclonal Antibody (7E2E6)


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Cat.No.:  EAb-2651
Product Name:  HDAC4 Monoclonal Antibody (7E2E6)
Product Overview:  Mouse monoclonal (7E2E6) to detect HDAC4
Antibody Type:  Monoclonal
Clone Designation:  7E2E6
Immunogen:  Recombinant fragment corresponding to Human HDAC4 aa 456-592. Expressed in E.coli.
Host:  Mouse
Isotype:  IgG1
Purification:  Protein G purified
Appearance:  Liquid
Formulation:  0.05% Sodium azide, PBS
Applications:  WB, Flow Cyt, ICC/IF
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  P56524
Alternative Name:  AHO3 antibody/BDMR antibody/EC 3.5.1.98 antibody
Scientific Background:  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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