PADI4/PAD4 Polyclonal Antibody


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Cat.No.:  EAb-2700
Product Name:  PADI4/PAD4 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect PADI4/PAD4
Antibody Type:  Polyclonal
Immunogen:  Recombinant fragment containing a sequence corresponding to a region within amino acids 326-581 of Human PADI4/ PAD4
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.00; 0.025% Proclin, PBS, 1% BSA, 20% Glycerol
Applications:  WB, IHC-P
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  AAH25718
Alternative Name:  EC 3.5.3.15 antibody/HL 60 PAD antibody/HL-60 PAD antibody
Scientific Background:  Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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