KDM4B/JMJD2B Monoclonal Antibody (3A6H6)


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Cat.No.:  EAb-2724
Product Name:  KDM4B/JMJD2B Monoclonal Antibody (3A6H6)
Product Overview:  Mouse monoclonal (3A6H6) to detect KDM4B/JMJD2B
Antibody Type:  Monoclonal
Clone Designation:  3A6H6
Immunogen:  Recombinant fragment corresponding to Human KDM4B/ JMJD2B aa 960-1096 (C terminal). Expressed in E. coli.
Immunogen Sequence:  NLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVE FEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAK RPRVGTPLATEDSGRSQDYVAFVESLLQVQGRPGAPF
Host:  Mouse
Isotype:  IgG1
Purification:  Protein G purified
Appearance:  Liquid
Formulation:  0.05% Sodium azide, PBS
Applications:  WB, Flow Cyt
Species Reactivity:  Mouse, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  O94953
Alternative Name:  JHDM3B antibody/JmjC domain-containing histone demethylation protein 3B antibody/JMJD2B antibody
Scientific Background:  Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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