Cat.No.: | EAb-2955 |
Product Name: | KDM5B/PLU1/Jarid1B Polyclonal Antibody |
Product Overview: | Rabbit polyclonal to detect KDM5B/PLU1/Jarid1B |
Antibody Type: | Polyclonal |
Immunogen: | Synthetic peptide corresponding to Mouse KDM5B/ PLU1/ Jarid1B (internal sequence) conjugated to keyhole limpet haemocyanin. |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Whole antiserum |
Appearance: | Liquid |
Formulation: | 0.05% Sodium azide |
Applications: | WB |
Species Reactivity: | Mouse |
Storage: | -20°C. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q80Y84 |
Alternative Name: | Cancer/testis antigen 31 antibody/CT31 antibody/Histone demethylase JARID1B antibody |
Scientific Background: | Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0002 | AT9283 | Inquiry |
◆ Cell Lines | ||
CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
◆ Antibodies | ||
EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
JADE1 | JAK | JAK1 | JAK2 |
JAK3 | JAKMIP1 | JARID | JARID1 |
JARID1A | JARID1B | JARID1C | JARID2 |
KDM1 | KDM1A | KDM1B | KDM2 |
KDM2A | KDM2B | KDM3A | KDM3B More > |
KDM4 | KDM4A | KDM4B | KDM4C |
KDM4D | KDM4E | KDM5 | KDM5A |
KDM5B | KDM5C | KDM5D | KDM6A |
KDM6B | KDM6C | KDM7 | KDM7A |
KDM7B | KDM8 | PLC | PLU1 |
PLZF |
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