KDM4A Polyclonal Antibody


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Cat.No.:  EAb-3425
Product Name:  KDM4A Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant fusion protein containing a sequence corresponding to amino acids 585-815 of human KDM4A
Immunogen Sequence:  FSLEENKKSKGRRQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSP
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  150kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB; IHC; IF; IP
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  BT-474,THP-1,Mouse thymus
Species Reactivity:  Human, Mouse, Rat
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot O75164; NP_055478.2; Gene ID 9682
Alternative Name:  KDM4A; JHDM3A; JMJD2; JMJD2A; TDRD14A; lysine demethylase 4A
Scientific Background:  This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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