| Cat.No.: | PE-0017 |
| Product Name: | Recombinant Human Histone Deacetylase 1, His-FLAG Tagged |
| Product Overview: | Recombinant Humanfull-length HDAC1 with C-terminal His-FLAG Tagged. |
| Description: | HDAC1belongs to the Histone Deacetylase/acuc/apha family and is a component of theHistone Deacetylase complex. HDAC1 interacts with Retinoblastomatumor-suppressor protein (Rb) and this complex is a key element in thecontrol of cell proliferation and differentiation. Together withMetastasis-Associated Protein-2, it deacetylates p53 and modulates its effecton cell growth and apoptosis. |
| Applications: | Enzyme kinetics; Screeninginhibitors; Selectivity profiling.The optimal concentration should bedetermined by the user for each specific application. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 56 kDa |
| Species: | Human |
| Formulation: | Liquid in 25 mMTris-HCl, pH 8.0 + 130 mM NaCl + 0.05% Tween-20 + 10% Glycerol. |
| Tag: | His & FLAG |
| Expression System: | Sf9 Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC1 histone deacetylase 1 [ Homosapiens ] |
| Gene ID NCBI: | 3065 |
| Synonyms: | HDAC1; histone deacetylase 1; DKFZp686H12203;GON-10; HD1; RPD3; RPD3L1; OTTHUMP00000008745; reduced potassium dependency,yeast homolog-like 1; DKFZp686H12203; EC 3.5.1.98 |
| mRNA Refseq: | NM_004964 |
| Protein Refseq: | NP_004955 |
| MIM: | 601241 |
| Chromosome Location: | 1p34 |
| Function: | enzyme binding; histonedeacetylase activity; hydrolase activity; identical protein binding;transcription activator activity; transcription factor activity;transcription factor binding; transcription factor binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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