| Cat.No.: | PE-0029 |
| Product Name: | Recombinant Human HDAC2, His-tagged |
| Product Overview: | Recombinant Human HDAC2, a single, non-glycosylated polypeptide chain fussed with His tag was expressed in Sf9 insect cells. |
| Description: | HDAC2 is a member of the histone deacetylase family that performs through the construction of large multiprotein complexes and are in charge of the deacetylation of lysine residues on the N-terminal region of the core histones. HDAC2 forms transcriptional repressor complexes by relating to a diversity of proteins, like YY1- a mammalian zinc-finger transcription factor. Additionally, HDAC2 has a vital part in transcriptional regulation, cell cycle progression and developmental procedures. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 56.2 kDa, observed by reducing SDS-PAGE. |
| Purity: | > 80% by SDS-PAGE analysis. |
| Species: | Human |
| Formulation: | The HDAC2 solution contains 20 mM Tris-HCl buffer (pH 8.0), 300 mM NaCl and 20% Glycerol. Frozen solution. |
| Tag: | His |
| Amino Acid Sequence: | MAYSQGGGKK KVCYYYDGDI GNYYYGQGHP MKPHRIRMTHNLLLNYGLYR KMEIYRPHKA TAEEMTKYHS DEYIKFLRSIRPDNMSEYSK QMQRFNVGED CPVFDGLFEF CQLSTGGSVAGAVKLNRQQT DMAVNWAGGL HHAKKSEASG FCYVNDIVLAILELLKYHQR VLYIDIDIHH GDGVEEAFYT TDRVMTVSFHKYGEYFPGTG DLRDIGAGKG KYYAVNFPMR DGIDDESYGQIFKPIISKVM EMYQPSAVVL QCGADSLSGD RLGCFNLTVKGHAKCVEVVK TFNLPLLMLG GGGYTIRNVA RCWTYETAVALDCEIPNELP YNDYFEYFGP DFKLHISPSN MTNQNTPEYMEKIKQRLFEN LRMLPHAPGV QMQAIPEDAV HEDSGDEDGEDPDKRISIRA SDKRIACDEE FSDSEDEGEG GRRNVADHKKGAKKARIEED KKETEDKKTD VKEEDKSKDN SGEKTDTKGTKSEQLSNPGH HHHHH |
| Endotoxin: | < 1 EU/μg, determined by LAL method. |
| Activity: | > 500 pmol/min/μg |
| Expression System: | Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC2 histone deacetylase 2 [ Homo sapiens ] |
| Gene ID NCBI: | 3066 |
| Synonyms: | HD2; RPD3; YAF1; histone deacetylase 2; YY1-associated factor 1; transcriptional regulator homolog RPD3 |
| mRNA Refseq: | NM_001527 |
| Protein Refseq: | NP_001518 |
| MIM: | 605164 |
| Chromosome Location: | 6q21 |
| Function: | Krueppel-associated box domain binding; NF-kappaB binding; core promoter binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
