Cat.No.: | PE-0041 |
Product Name: | Recombinant Human Histone Deacetylase 3, GST-tagged |
Product Overview: | Full-length recombinant human HDAC3 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag. |
Description: | HDAC3 or Histone deacetylase 3 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex that represses transcription when tethered to a promoter. HDAC3 may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. |
Applications: | HDAC Assay; Western Blot |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Molecular Weight: | 83 kDa |
Purity: | >70% |
Species: | Human |
Formulation: | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Tag: | GST |
Activity: | 125 RLU/min/ng |
Expression System: | Sf9 Insect Cells |
Protein Length: | Full length |
Concentrations: | 0.1 ug/ul |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name: | HDAC3 histone deacetylase 3 [ Homo sapiens ] |
Gene ID NCBI: | 8841 |
Official Symbol: | HDAC3 |
Synonyms: | HDAC3; histone deacetylase 3; HD3; RPD3; RPD3-2; histone deacetylase 3; SMAP45; OTTHUMP00000160029 |
mRNA Refseq: | NM_003883 |
Protein Refseq: | NP_003874 |
MIM: | 605166 |
UniProt ID: | O15379 |
Chromosome Location: | 5q31.1-q31 |
Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; transcription factor binding; chromatin binding; DNA binding; protein deacetylase activity; transcription corepressor activity |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
◆ Bioactive Small Molecules | ||
BSM-0007 | Tubacin | Inquiry |
Related Gene / Proteins | |||
HDAC | HDAC1 | HDAC10 | HDAC11 |
HDAC2 | HDAC3 | hdac4 | hdac5 |
HDAC6 | hdac7 | HDAC8 | hdac9 |
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