| Cat.No.: | PE-0078 |
| Product Name: | Recombinant Human HDAC6 (Active), GST-tagged |
| Product Overview: | Recombinant full-length human HDAC6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | HDAC6 or Histone deacetylase 6 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. The protein encoded by this gene belongs to class II of the histone deacetylase family that regulates important biologic processes beyond histone metabolism and gene transcription. HDAC6 is a central component of the stress response that regulates SG formation and potentially contributes to control of RNA metabolism and translation. |
| Applications: | HDAC Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~ 180 kDa |
| Purity: | >80% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Activity: | 5800 nmol/min/mg |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full length |
| Concentrations: | 0.1 μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC6 histone deacetylase 6 [ Homo sapiens ] |
| Gene ID NCBI: | 10013 |
| Synonyms: | HDAC6; histone deacetylase 6; FLJ16239; HD6; JM21; KIAA0901; |
| mRNA Refseq: | NM_006044 |
| Protein Refseq: | NP_006035 |
| MIM: | 300272 |
| UniProt ID: | Q9UBN7 |
| Chromosome Location: | Xp11.23 |
| Function: | Hsp90 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); actin binding; alpha-tubulin binding; beta-catenin binding; beta-tubulin binding; dynein complex binding; enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; metal ion binding; microtubule binding; microtubule binding; polyubiquitin binding; protein binding; tau protein binding; tubulin deacetylase activity; tubulin deacetylase activity; zinc ion binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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