| Cat.No.: | PE-0099 |
| Product Name: | Recombinant Human Histone Deacetylase 8, His-tagged |
| Product Overview: | Full-length recombinant human HDAC8 was expressed by baculovirus in Sf9 insect cells using a C-terminal His tag. |
| Description: | HDAC8 or Histone deacetylase 8 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by this gene belongs to class I of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. |
| Applications: | HDAC Assay; Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 47 kDa |
| Purity: | >90% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50 mM MOPS, PH 7.0, 300 mM NaCI, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Tag: | His |
| Activity: | 1400 RLU/min/ng |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full length |
| Concentrations: | 0.05 ug/ul |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC8 histone deacetylase 8 [ Homo sapiens ] |
| Gene ID NCBI: | 55869 |
| Official Symbol: | HDAC8 |
| Synonyms: | HDAC8; histone deacetylase 8; HD8; RPD3; CDA07; HDACL1; histone deacetylase 8; OTTHUMP00000023539; OTTHUMP00000023540; OTTHUMP00000023541; OTTHUMP00000023542; OTTHUMP00000023543; OTTHUMP00000023544; OTTHUMP00000023545; OTTHUMP00000023546; OTTHUMP00000023549; histone deacetylase-like 1 |
| mRNA Refseq: | NM_001166418 |
| Protein Refseq: | NP_001159890 |
| MIM: | 300269 |
| UniProt ID: | Q9BY41 |
| Chromosome Location: | Xq13 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; metal ion binding; histone deacetylase activity |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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