| Cat.No.: | PE-0109 |
| Product Name: | Recombinant Human HDAC10 (Active), GST-tagged |
| Product Overview: | Recombinant human HDAC10 (1-482) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | HDAC10 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC10 belongs to class II of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the N-terminal tail of histones and represses transcription in large multiprotein complexes with transcriptional co-repressors. Therefore, HDAC10 plays a role in transcriptional repression. HDAC10 interacts with HDAC3 in co-transfected embryonic kidney cells. Deletion analysis indicates that both the N- and C-terminal domains of HDAC10 bound HDAC3 independently. |
| Applications: | HDAC Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~77 kDa |
| Purity: | >80% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Activity: | 120 RLU/min/ng |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 1-482 aa |
| Concentrations: | 0.1μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC10 histone deacetylase 10 [ Homo sapiens ] |
| Gene ID NCBI: | 83933 |
| Synonyms: | HDAC10; histone deacetylase 10; DKFZP761B039; HD10; MGC149722; DKFZp761B039; |
| mRNA Refseq: | NM_001159286 |
| Protein Refseq: | NP_001152758 |
| MIM: | 608544 |
| UniProt ID: | Q969S8 |
| Chromosome Location: | 22q13.31 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
