| Cat.No.: | PE-0113 |
| Product Name: | Recombinant Human HDAC10 protein, FLAG-tagged |
| Product Overview: | Recombinant Human HDAC10(a.a. 2-631) fused with FLAG tag at N-terminal was expressed in Insect cells. |
| Description: | The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 67 kDa |
| Species: | Human |
| Formulation: | 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 0.05% Tween-20 and 10% glycerol. |
| Tag: | FLAG |
| Activity: | >3.6 pmol/min/μg. |
| Expression System: | Insect Cells |
| Concentrations: | 0.15 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC10 histone deacetylase 10 [ Homo sapiens ] |
| Gene ID NCBI: | 83933 |
| Official Symbol: | HDAC10 |
| Synonyms: | HDAC10; histone deacetylase 10; DKFZP761B039; HD10; MGC149722; DKFZp761B039; |
| mRNA Refseq: | NM_032019 |
| Protein Refseq: | NP_114408 |
| MIM: | 608544 |
| UniProt ID: | Q969S8 |
| Chromosome Location: | 22q13.31 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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