| Cat.No.: | PE-0474 |
| Product Name: | Recombinant Human Histone Deacetylase 9, His-tagged |
| Product Overview: | Recombinant human HDAC9 (548-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | HDAC9 or MIRT belongs to the histone deacetylase /acuc/apha family and is a component of the histone deacetylase complex. HDAC9 gene is orthologous to the Xenopus and mouse MITR genes (MEF2-interacting transcription repressor). HDAC9 represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 is a calcium-sensitive transcriptional repressor of MEF2. |
| Applications: | HDAC Assay; Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 77 kDa |
| Purity: | >80% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Tag: | His |
| Activity: | 235 RLU/min/ng |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 548-end |
| Concentrations: | 0.1 ug/ul |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC9 histone deacetylase 9 [ Homo sapiens ] |
| Gene ID NCBI: | 9734 |
| Official Symbol: | HDAC9 |
| Synonyms: | HDAC9; histone deacetylase 9; HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL; KIAA0744; DKFZp779K1053; histone deacetylase 9; OTTHUMP00000201766; OTTHUMP00000201767; OTTHUMP00000201768; OTTHUMP00000201895; OTTHUMP00000201926; OTTHUMP00000201927; OTTHUMP00000225210; OTTHUMP00000225211; OTTHUMP00000225262; OTTHUMP00000231731; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein |
| mRNA Refseq: | NM_178423 |
| Protein Refseq: | NP_848510 |
| MIM: | 606543 |
| UniProt ID: | Q9UKV0 |
| Chromosome Location: | 7p21 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; histone deacetylase binding; protein binding; protein deacetylase activity; protein kinase C binding; repressing transcription factor binding; NOT histone deacetylase activity; protein kinase C binding; transcription corepressor activity; histone deacetylase activity |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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