Cat.No.: | PE-0674 |
Product Name: | Recombinant Human Upstream Transcription Factor 1 |
Description: | Human Upstream Stimulatory Factor 1 (USF1) regulates the transcription of many genes involved in lipid and glucose homeostasis and co-localizes with familial combined hyperlipidemia (FCHL) and type 2-diabetes on chromosome 1q22-23. The USF1 protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. It is a basic helix-loop-helix leucine zipper (b-HLH-ZIP) protein that shares a common DNA-binding specificity with the c-Myc oncoproteins. |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Purity: | >95% by SDS-PAGE. |
Species: | Human |
Formulation: | Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 20% glycerol, 100 mM KCl, 0.2 mM EDTA and 1 mM DTT. |
Activity: | 5-50 ng are sufficient for DNA binding assays, 50-500 ng are required for in vitro transcription assays and 100 ng are required for protein-protein interaction assays. |
Expression System: | E. coli |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name: | USF1 upstream transcription factor 1 [ Homo sapiens ] |
Gene ID NCBI: | 7391 |
Synonyms: | USF1; upstream transcription factor 1; UEF; FCHL; MLTF; FCHL1; MLTFI; HYPLIP1; bHLHb11; OTTHUMP00000029691; OTTHUMP00000029693; USF; Major late transcription factor 1; upstream stimulatory factor 1 |
mRNA Refseq: | NM_007122 |
Protein Refseq: | NP_009053 |
MIM: | 191523 |
UniProt ID: | P22415 |
Chromosome Location: | 1q22-q23 |
Function: | RNA polymerase II transcription factor activity, enhancer binding; RNA polymerase II transcription factor activity, enhancer binding; bHLH transcription factor binding; double-stranded DNA binding; histone deacetylase binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; protein kinase binding; sequence-specific DNA binding; transcription activator activity |
Product Types | ||
◆ Antibodies | ||
EAb-0006 | USP3 Polyclonal Antibody | Inquiry |
EAb-0007 | USP25 Polyclonal Antibody | Inquiry |
EAb-0008 | USP2 Polyclonal Antibody | Inquiry |
EAb-0009 | USP1 Polyclonal Antibody | Inquiry |
EAb-0010 | USP7 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
USF1 | USP1 | USP10 | USP11 |
USP12 | USP13 | USP14 | USP15 |
USP16 | USP17L11 | USP17L12 | USP17L13 |
USP17L15 | USP17L17 | USP17L1P | USP17L2 |
USP17L22 | USP17L28 | USP17L3 | USP17L5 More > |
USP17L8 | USP18 | USP19 | USP2 |
USP20 | USP21 | USP22 | USP24 |
USP25 | USP26 | USP27X | USP28 |
USP29 | USP3 | USP30 | USP31 |
USP32 | USP33 | USP34 | USP35 |
USP36 | USP37 | USP38 | USP40 |
USP42 | USP43 | USP44 | USP45 |
USP46 | USP47 | USP48 | USP49 |
USP5 | USP53 | USP54 | USP6 |
USP6NL | USP7 | USP8 | USP9X |
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