Recombinant human USF1, His-tagged


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  • Gene Information
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Cat.No.:  PE-0677
Product Name:  Recombinant human USF1, His-tagged
Product Overview:  Recombinant human USF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description:  USF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. USF1 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.
Applications:  SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight:  35.9kDa (333aa), confirmed by MALDI-TOF
Purity:  >90% by SDS - PAGE
Species:  Human
Formulation:  Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Tag:  His
Amino Acid Sequence:  MGSSHHHHHH SSGLVPRGSH MGSMKGQQKT AETEEGTVQI QEGAVATGED PTSVAIASIQ SAATFPDPNV KYVFRTENGG QVMYRVIQVS EGQLDGQTEG TGAISGYPAT QSMTQAVIQG AFTSDDAVDT EGTAAETHYT YFPSTAVGDG AGGTTSGSTA AVVTTQGSEA LLGQATPPGT GQFFVMMSPQ EVLQGGSQRS IAPRTHPYSP KSEAPRTTRD EKRRAQHNEV ERRRRDKINN WIVQLSKIIP DCSMESTKSG QSKGGILSKA CDYIQELRQS NHRLSEELQG LDQLQLDNDV LRQQVEDLKN KNLLLRAQLR HHGLEVVIKN DSN
Expression System:  E. coli
Concentrations:  0.25 mg/ml (determined by Bradford assay)
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name:  USF1 upstream transcription factor 1 [ Homo sapiens ]
Gene ID NCBI:  7391
Synonyms:  USF1; upstream transcription factor 1; upstream stimulatory factor 1; bHLHb11; MLTFI; UEF; major late transcription factor 1; class B basic helix-loop-helix protein 11; FCHL; MLTF; FCHL1; HYPLIP1;
mRNA Refseq:  NM_007122
Protein Refseq:  NP_009053
MIM:  191523
UniProt ID:  P22415
Chromosome Location:  1q22-q23
Function:  bHLH transcription factor binding; double-stranded DNA binding; enzyme binding; histone deacetylase binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; protein kinase binding

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