Recombinant Human SUZ12


  • Specification
  • Gene Information
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Cat.No.:  PE-0802
Product Name:  Recombinant Human SUZ12
Product Overview:  Recombinant fragment corresponding to amino acids 640-739 of Human SUZ12 with a propreitary tag at N-terminal; predicted mwt: 36.63 kDa.
Description:  This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
Tissue Specificity:  Overexpressed in breast and colon cancer.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  36.630kDa inclusive of tags
Species:  Human
Amino Acid Sequence:  VENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL
Sequence Similarities:  Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.Contains 1 C2H2-type zinc finger.
Expression System:  Wheat germ
Protein Length:  100 amino acids
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name:  SUZ12 suppressor of zeste 12 homolog (Drosophila) [ Homo sapiens ]
Gene ID NCBI:  23512
Official Symbol:  SUZ12
Synonyms:  SUZ12; suppressor of zeste 12 homolog (Drosophila); polycomb protein SUZ12; CHET9; JJAZ1; KIAA0160;
mRNA Refseq:  NM_015355
Protein Refseq:  NP_056170
MIM:  606245
UniProt ID:  Q15022
Chromosome Location:  17q21
Function:  chromatin binding; histone methyltransferase activity; metal ion binding; methylated histone residue binding; protein binding;

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