| Cat.No.: | PE-0898 |
| Product Name: | Recombinant Human Regulator Of Chromosome Condensation 1 |
| Description: | RCC1 (Regulator of Chromosome Condensation, α βpropeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran. MW = 44.97 kDa. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | ≥95% by SDS-PAGE. |
| Species: | Human |
| Formulation: | Liquid. Supplied in 20 mM HEPES pH 7.6, 50 mM NaCl and 2 mM DTE. |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | RCC1 regulator of chromosome condensation 1 [ Homo sapiens ] |
| Gene ID NCBI: | 1104 |
| Synonyms: | regulator of chromosome condensation 1; CHC1; RCC1-I; RCC1; OTTHUMP00000003775; chromosome condensation 1; guanine nucleotide-releasing protein; HERC2; SHEP1 ; OTTHUMP00000003775; OTTHUMP00000003776; OTTHUMP00000003777; Cell cycle regulatory protein; Chromosome condensation protein 1 |
| mRNA Refseq: | NM_001048194 |
| Protein Refseq: | NP_001041659 |
| MIM: | 179710 |
| UniProt ID: | P18754 |
| Chromosome Location: | 1p35.3 |
| Function: | Ran guanyl-nucleotide exchange factor activity; chromatin binding; guanyl-nucleotide exchange factor activity; histone binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0116 | Recombinant Human RCC1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0898 | Recombinant Human Regulator Of Chromosome Condensation 1 | Inquiry |
| PE-0899 | Recombinant Human RCC1, GST-tagged | Inquiry |
| PE-0900 | Recombinant Zebrafish RCC1 | Inquiry |
| PE-0901 | Recombinant Human RCC1 Protein, Strep-tagged | Inquiry |
| Related Gene / Proteins | |||
| RCC1 | |||
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