Recombinant Human CDK1


  • Specification
  • Gene Information
  • Related Products
Cat.No.:  PE-0924
Product Name:  Recombinant Human CDK1
Product Overview:  Recombinant full length Human CDK1 and CCNB1 with N terminal proprietary tags on both proteins; MWt 58 and 75kDa respectively.
Description:  The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Tissue Specificity:  Isoform 2 is found in breast cancer tissues.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Sequence Similarities:  Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.Contains 1 protein kinase domain.
Activity:  The Specific activity of CCNB1-31593TH was determined to be 14 nmol/min/mg.
Expression System:  Sf9 Insect Cells
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name:  CCNB1 cyclin B1 [ Homo sapiens ]
Gene ID NCBI:  891
Official Symbol:  CCNB1
Synonyms:  CCNB1; cyclin B1; CCNB; G2/mitotic-specific cyclin-B1; G2/mitotic specific cyclin B1;
mRNA Refseq:  NM_031966
Protein Refseq:  NP_114172
MIM:  123836
UniProt ID:  P14635
Chromosome Location:  5q12
Function:  histone kinase activity; kinase activity; protein binding; protein kinase binding;

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