| Cat.No.: | PE-1073 |
| Product Name: | Recombinant Human SUV420H1, GST-tagged |
| Product Overview: | Recombinant Human SUV420H1, amino acids 2-387 with N-terminal GST tag expressed in E.Coli expression system. MW = 70kDa. |
| Description: | Histone-lysine N-methyltransferase SUV420H1 is an enzyme that in humans is encoded by the SUV420H1 gene.This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >20%. |
| Species: | Human |
| Formulation: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) [ Homo sapiens ] |
| Gene ID NCBI: | 51111 |
| Synonyms: | SUV420H1; suppressor of variegation 4-20 homolog 1 (Drosophila); CGI85; KMT5B; CGI-85; MGC703; MGC21161; MGC118906; MGC118909; OTTHUMP00000197482; OTTHUMP00000197488; C630029K18Rik; EC 2.1.1.43 |
| mRNA Refseq: | NM_016028 |
| Protein Refseq: | NP_057112 |
| MIM: | 610881 |
| UniProt ID: | Q4FZB7 |
| Chromosome Location: | 11q13.2 |
| Function: | histone methyltransferase activity (H4-K20 specific); protein binding; transferase activity |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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