Recombinant Human KDM4D, FLAG-tagged


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Cat.No.:  PE-1370
Product Name:  Recombinant Human KDM4D, FLAG-tagged
Product Overview:  Recombinant Human KDM4D (accession number NP_060509.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 63.2 kDa.
Description:  KDM4D (lysine (K)-specific demethylase 4D), also known as JMJD2D (Jumonji Domain Containing 2D) is a protein that functions as a histone demethylase that preferentially demethylates di- and trimethylated lysine 9 residues of histone H3, while it has no activity on monomethylated H3K9 residues.
Applications:  Enzyme kinetics, inhibitor screening, and selectivity profiling.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Species:  Human
Formulation:  25 mM HEPES, pH 7.5, 150 mM NaCl and 5% glycerol.
Tag:  FLAG
Activity:  H3K9me3 demethylase.
Expression System:  Sf9 Insect Cells
Concentrations:  0.8 mg/ml
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name:  KDM4D lysine (K)-specific demethylase 4D [ Homo sapiens ]
Gene ID NCBI:  55693
Synonyms:  KDM4D; lysine (K)-specific demethylase 4D; JMJD2D, jumonji domain containing 2D; lysine-specific demethylase 4D; FLJ10251; jumonji domain containing 2D; jumonji domain-containing protein 2D; jmjC domain-containing histone demethylation protein 3D; JMJD2D; MGC141909;
mRNA Refseq:  NM_018039
Protein Refseq:  NP_060509
MIM:  609766
UniProt ID:  Q6B0I6
Chromosome Location:  11q21
Function:  metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;

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