| Cat.No.: | PE-1387 |
| Product Name: | Recombinant Human KDM5A Protein, DDK-tagged |
| Product Overview: | Recombinant Human KDM5A fused with DDK tag at C-terminal was expressed in HEK293 cells. |
| Description: | This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 192 kDa |
| Purity: | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Species: | Human |
| Formulation: | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. |
| Tag: | DDK |
| Expression System: | HEK293 |
| Concentrations: | >50 ug/mL as determined by microplate BCA method |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KDM5A lysine (K)-specific demethylase 5A [ Homo sapiens ] |
| Gene ID NCBI: | 5927 |
| Official Symbol: | KDM5A |
| Synonyms: | KDM5A; lysine (K)-specific demethylase 5A; JARID1A, jumonji, AT rich interactive domain 1A , Jumonji, AT rich interactive domain 1A (RBBP2 like) , RBBP2, retinoblastoma binding protein 2; lysine-specific demethylase 5A; histone demethylase JARID1A; retinoblastoma binding protein 2; retinoblastoma-binding protein 2; jumonji/ARID domain-containing protein 1A; Jumonji, AT rich interactive domain 1A (RBP2-like); Jumonji, AT rich interactive domain 1A (RBBP2-like); RBP2; RBBP2; RBBP-2; JARID1A; |
| mRNA Refseq: | NM_001042603 |
| Protein Refseq: | NP_001036068 |
| MIM: | 180202 |
| UniProt ID: | P29375 |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
| CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
| CL-0089 | Human KDM2B Knockout Cell Line 14bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A More > |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | ||
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