| Cat.No.: | PE-1636 |
| Product Name: | EZH2/SUZ12/RbAp48, His-GST-tags, His-tag |
| Product Overview: | Complex of human EZH2 (GenBank Accession No. NM_004456), a.a. 2-end with N-terminal His-GST-tag, MW= 114 kDa, human SUZ12 (NM_015355), a.a. 1-end with N-terminal His-tag, MW = 87 kDa, and human RbAp48 (NM_005610), a.a. 2-end with N-terminal His-tag, MW= 48 kDa. Co-expressed in a baculovirus expression system. |
| Applications: | Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex. Requires EED protein for methyltransferase activity. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 249 kDa (complex) |
| Species: | Human |
| Formulation: | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 3mM DTT, and 20% glycerol. |
| Tag: | His-GST & His |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 2–end (EZH2, RbAp48), 1–end (SUZ12) |
| Format: | Aqueous buffer solution |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene ID NCBI: | NM_004456 (EZH2), NM_015355 (SUZ12), NM_005610 (RbAP48) |
| Synonyms: | KTM6, KTM6A, EZH2, PRC2, Enhancer Of Zeste Homolog 2; SUZ12, Suppressor Of Zeste 12 Homolog, CHET9, JJAZ1; RBAP48, Retinoblastoma Binding Protein 4 (RBBP4), NURF55, Chromatin Assembly Factor 1 Subunit C, CAF1 p48, EZH |
| UniProt ID: | Q15910 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| EAb-0043 | RBBP4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ezh1 | EZH2 | RB1 | RbAp46 |
| RbAp48 | RBB4L | RBBP2 | RBBP4 |
| RBBP5 | RBBP7 | RBBP9 | RBM11 |
| RBM18 | RBM26 | RBM3 | RBM34 |
| RBM38 | RBM39 | RBM41 | RBM42 More > |
| RBM46 | RBM5 | RBM7 | RBMS1 |
| RBMS2 | RBMS3 | RBMY1A1 | RBMY1F |
| RBPJ | RBPMS | SUDS3 | SUMO |
| SUMO1 | SUMO2 | SUMO3 | SUN1 |
| Surf6 | suv39h1 | SUV39H2 | SUV3L1 |
| SUV420H1 | SUV420H2 | SUZ12 | |
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