| Cat.No.: | PE-1638 |
| Product Name: | EZH2/EED/SUZ12/RbAp48, His-tag, FLAG-tag |
| Product Overview: | Complex of human EZH2 (GenBank Accession No. NM_004456), a.a. 2-end with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797), a.a. 2-end with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355), a.a. 2-end with N-terminal His-tag, MW = 87 kDa, and human RbAp48 (NM_005610), a.a. 2-end with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 272 kDa (complex) |
| Species: | Human |
| Formulation: | 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 225 mM imidazole, and 10% glycerol. |
| Tag: | His & FLAG |
| Activity: | 0.046 pmol/min/µg |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 2–end (all components) |
| Format: | Aqueous buffer solution |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene ID NCBI: | NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_005610(RbAP48) |
| Synonyms: | KTM6A, EZH2, PRC2, Enhancer Of Zeste Homolog 2; RBAP48, Retinoblastoma Binding Protein 4 (RBBP4), NURF55, Chromatin Assembly Factor 1 Subunit C, CAF1 p48; Embryonic Ectoderm Development, hEED, EED, WAIT-1; SUZ12, Suppressor Of Zeste 12 Homolog, CHET9, JJA |
| UniProt ID: | Q15910 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| EL-0026 | Recombinant Human EED Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| EED | EEF1A1 | EEF1A2 | EEF1B2 |
| EEF1G | ezh1 | EZH2 | RB1 |
| RbAp46 | RbAp48 | RBB4L | RBBP2 |
| RBBP4 | RBBP5 | RBBP7 | RBBP9 |
| RBM11 | RBM18 | RBM26 | RBM3 More > |
| RBM34 | RBM38 | RBM39 | RBM41 |
| RBM42 | RBM46 | RBM5 | RBM7 |
| RBMS1 | RBMS2 | RBMS3 | RBMY1A1 |
| RBMY1F | RBPJ | RBPMS | SUDS3 |
| SUMO | SUMO1 | SUMO2 | SUMO3 |
| SUN1 | Surf6 | suv39h1 | SUV39H2 |
| SUV3L1 | SUV420H1 | SUV420H2 | SUZ12 |
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