| Cat.No.: | PE-1649 |
| Product Name: | EZH2 (R679C)/EED/SUZH12/RbAp48/AEBP2, FLAG-tag, His-tag |
| Product Overview: | Complex of human EZH2 (GenBank Accession No. NM_004456), (a.a. 2-end ; R684C) with N-terminal His-tag, MW= 86kDa, human EED (NM_003797) (a.a. 2-end) with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355) (a.a. 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (NM_153207) (a.a. 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (NM_005610) (a.a. 2-end) with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system. *This mutation is equivalent to R679C in variant 3 (GenBank Accession No. NM_001203247). |
| Applications: | Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 325 kDa (complex) |
| Species: | Human |
| Formulation: | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol |
| Tag: | FLAG & His |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 2–end (all components) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene ID NCBI: | NM_004456 (EZH2), NM_003797(EED), NM_015355 (SUZ12), NM_153207(AEBP2), NM_005610(RbAP48) |
| Synonyms: | KTM6A, EZH2, PRC2, Enhancer Of Zeste Homolog 2, RBAP48, Retinoblastoma Binding Protein 4 (RBBP4), hEED, Suppressor Of Zeste 12 Homolog, CHET9, JJAZ1; AE binding protein 2, Adipocyte Enhancer binding protein 2, EZH |
| UniProt ID: | Q15910 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| EL-0026 | Recombinant Human EED Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| AEBP2 | EED | EEF1A1 | EEF1A2 |
| EEF1B2 | EEF1G | ezh1 | EZH2 |
| RB1 | RbAp46 | RbAp48 | RBB4L |
| RBBP2 | RBBP4 | RBBP5 | RBBP7 |
| RBBP9 | RBM11 | RBM18 | RBM26 More > |
| RBM3 | RBM34 | RBM38 | RBM39 |
| RBM41 | RBM42 | RBM46 | RBM5 |
| RBM7 | RBMS1 | RBMS2 | RBMS3 |
| RBMY1A1 | RBMY1F | RBPJ | RBPMS |
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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