Recombinant Human MBD4/MED1 protein


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Cat.No.:  PE-2980
Product Name:  Recombinant Human MBD4/MED1 protein
Background:  Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
Applications:  SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Lyophilised
Molecular Weight:  26 kDa
Species:  Human
Formulation:  Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
Accession#:  O95243
Alternative Names:  3 N(4) ethenocytosine glycosylase/G/5 fluorouracil mismatch glycosylase with biphasic kinetics/G/T mismatch glycosylase
Sequence Similarities:  Contains 1 MBD (methyl-CpG-binding) domain.
Expression System:  E. coli
Protein Length:  Protein fragment; 68 to 300
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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