| Cat.No.: | PE-3739 |
| Product Name: | MBD4 recombinant protein |
| Description: | Active full length recombinant human N-terminal His tagged MBD4 (Methyl-CpG Binding Domain Protein 4)protein, produced in SF9 insect cells. |
| Background: | MBD4 (UniProt/Swiss-Prot entry O95243) belongs to the family of methyl CpG binding proteins that specifically bind to methylatedCpG dinucleotides. MBD4 probably functions to mediate the biological consequences of CpG methylation. Further, MBD4 hasthymine glycosylase activity and is involved in DNA mismatch repair. It is specific for G/T mismatches within methylated andunmethylated CpG sites Mutations of MBD4 are associated with tumors with primary microsatellite-instability, a type of genomicinstability that is caused by a defective DNA mismatch repair. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | Purified using FPLC, >95% purity as determined by SDS-PAGE. |
| Species: | Human |
| Formulation: | 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 MNaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT. |
| Alternative Names: | MED1 |
| Tag: | His |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.5 µg/µl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0001 | Recombinant Human MBD1 Cell Lysate | Inquiry |
| EL-0002 | Recombinant Human MBD3 Cell Lysate | Inquiry |
| EL-0003 | Recombinant Human MBD3L1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0001 | Recombinant Chicken MBD2 | Inquiry |
| PE-0002 | Recombinant Zebrafish MBD2 | Inquiry |
| Related Gene / Proteins | |||
| MBD1 | mbd2 | MBD3 | MBD3L1 |
| MBD3L2 | MBD3L3 | MBD3L4 | MBD3L5 |
| MBD4 | MBD5 | MBD6 | MBIP |
| MBTD1 | |||
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