RVX-208


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Cat.No.:  BSM-0046
Product Name:  RVX-208
CAS No.:  1044870-39-4
Figure: 
Synonyms:  2-{4-(2-hydroxyethoxy)-3,5-dimethylphenyl}-5,7-dimethoxy-4(3H)-quinazolinone
Description:  RVX-208 is a potent BET bromodomain antagonist with (IC50 = 0.51 µM for BD2) with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis.
Appearance:  White powder.
Molecular Weight:  370.4
Purity:  >98% (TLC); NMR (Conforms)
Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month.
Targets:  BET Bromodomain
Molecular Formula:  C20H22N2O5
Solubility:  Dissolved in DMSO (75 mg/ml); Ethanol (4 mg/ml).
Warning:  For Research Use Only! Not For Use in Humans.
Product Types
◆ Synthetic Peptides
SP-0005 BET Bromodomain Ligand Inquiry
◆ Bioactive Small Molecules
BSM-0046 RVX-208 Inquiry
BSM-0055 (-)-JQ1 Inquiry
BSM-0081 AZD-5153 Inquiry
BSM-0090 BMS-986158 Inquiry
Related Gene / Proteins
BET

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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