| Cat.No.: | BSM-0128 |
| Product Name: | EPZ004777 |
| CAS No.: | 1338466-77-5 |
| Figure: |
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| Synonyms: | 1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea |
| Description: | EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 400 pM. Treatment of leukemic cells with EPZ004777 results in selective killing of those cells bearing the MLL (mixed lineage leukemia) gene translocation, with little effect on non-MLL-translocated cells. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 539.67 |
| Purity: | ≥98% by HPLC |
| Storage: | -20 ̊C |
| Targets: | DOT1L |
| Molecular Formula: | C28H41N7O4 |
| MDL Number: | MFCD00149494 |
| Solubility: | DMSO |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
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