| Cat.No.: | BSM-0274 |
| Product Name: | I-BET151 (GSK1210151A) |
| CAS No.: | 1300031-49-5 |
| Figure: |
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| Synonyms: | I-BET151; GSK1210151A; 7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one |
| Description: | I-BET151(GSK1210151A) is a BET bromodomain inhibitor. I-BET151 displays potent binding affinity to BRD2, BRD3 and BRD4 with Kd of 0.02-0.1 µM. I-BET151 (0.5 or 5 µM) inhibits the binding of BETs (BRD2, BRD3, BRD4, and BRD9) but not the binding of 23 other bromodomain proteins. I-BET151 also blocks recruitment of BET to chromatin. |
| Molecular Weight: | 415.4 |
| Storage: | -20°C |
| Targets: | BET |
| Molecular Formula: | C23H21N5O3 |
| Solubility: | Soluble in DMSO 83 mg/ml (199 mM), water < 1 mg/ml (<1 mM), ethanol 27 mg/ml (64 mM) |
| Warning: | For Research Use Only! Not For Use in Humans. |
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