Butyrolactone 3


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Cat.No.:  BSM-0299
Product Name:  Butyrolactone 3
CAS No.:  778649-18-6
Figure: 
Product Overview:  A HAT inhibitor
Description:  Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 μM and has an affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 can inhibit pre-RNA splicing with an IC50 value of 0.5 mM and as such has been used to investigate Gcn5/PCAF-like HAT functions during assembly of spliceosome before pre-mRNA translation.
Appearance:  A crystalline solid
Molecular Weight:  184.2
Purity:  ≥95%
Storage:  -20°C
Targets:  HAT
Molecular Formula:  C9H12O4
Chemical Name:  rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid
Warning:  For Research Use Only! Not For Use in Humans.
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Related Gene / Proteins
GCN5 PCAF PCBP2 PCBP3
PCBP4 PCGF2 PCGF6 PCL2
PCNA

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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