| Cat.No.: | EL-0336 |
| Product Name: | ZR-75-1 nuclear extract |
| Description: | ZR-75-1 nuclear extract was prepared from cell cultures of the human breast carcinoma ZR-75-1 cell line. The ZR-75-1 cell line was derived from a malignant effusion in a 63-year old Caucasian female patient with infiltrating ductal carcinoma. These epithelial-like cells express both wild type and mutant receptors to estradiol, receptors to progesterone, as well as other steroids. In addition, high levels of mRNA expression of the human tumor antigen MUC-1 has been observed in ZR-75-1 cells. The ZR-75-1 cell line is commonly used in research as in vitro model for studies of breast cancer tumorigenicity and related drug therapies, such as tamoxifen. |
| Species: | Human |
| Source: | Human breast carcinoma |
| Components: | 200 µg of ZR-75-1 nuclear extract at 5.4 µg/µl. |
| Extract Composition: | ZR-75-1 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT). |
| Application Notes: | ZR-75-1 nuclear extract is specifically recommended for use in studies related to breast cancer and associated drug therapies. |
| Storage: | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Warning: | For research use only, not for diagnostic or therapeutic use. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0001 | Recombinant Human MBD1 Cell Lysate | Inquiry |
| EL-0002 | Recombinant Human MBD3 Cell Lysate | Inquiry |
| EL-0003 | Recombinant Human MBD3L1 293 Cell Lysate | Inquiry |
| EL-0004 | Recombinant Human MBD4 Lysate | Inquiry |
| EL-0005 | Recombinant Human MBD5 Cell Lysate | Inquiry |
USA
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