Cat.No.: | EL-0343 |
Product Name: | U-937 nuclear extract |
Description: | U-937 nuclear extract was prepared from cell cultures of the human histiotic lymphoma U-937 cell line. The U-937 cell line was derived from malignant cells of a pleural effusion of a 37-year old male patient. These cells are of myeloid lineage and differentiate into a mature macrophage phenotype in response to various stimuli. U-937 cells produce and secrete large quantities of cytokines and chemokines either spontaneously or in response to treatment with soluble stimuli, such as TNFα. In addition, IFNβ and IFNϒ stimulation has been shown to induce the expression of chemokine receptors on the cell surface of U-937 cells and results in increased production of interleukins. Because U-937 cells are one of only a few human cell lines with characteristic monocytic properties, they are commonly used in research as in vitro models for monocyte/macrophage differentiation. |
Species: | Human |
Source: | Human histiocytic leukemia |
Components: | 200 µg of U-937 nuclear extract at 4.42 µg/µl. |
Extract Composition: | U-937 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT). |
Application Notes: | U-937 nuclear extract is recommended for studies of monocyte/macrophage differentiation. |
Storage: | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Warning: | For research use only, not for diagnostic or therapeutic use. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0001 | Recombinant Human MBD1 Cell Lysate | Inquiry |
EL-0002 | Recombinant Human MBD3 Cell Lysate | Inquiry |
EL-0003 | Recombinant Human MBD3L1 293 Cell Lysate | Inquiry |
EL-0004 | Recombinant Human MBD4 Lysate | Inquiry |
EL-0005 | Recombinant Human MBD5 Cell Lysate | Inquiry |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools