PC-3 nuclear extract


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Cat.No.:  EL-0358
Product Name:  PC-3 nuclear extract
Description:  PC-3 nuclear extract was prepared from cell cultures of the human prostate adenocarcinoma PC-3 cell line. The PC-3 cell line was derived from an advanced androgen-independent bone metastasis of a 64 year old Caucasian male patient with Grade IV prostatic cancer. PC-3 cells are considered the 'classical' prostate tumor cell line and are characterized by a high metastatic potential, the expression of Prostate Specific Antigen (PSA), and low acid phosphatase and testosterone-5-α reductase activity. PC-3 cells are most commonly used in research as a model of prostate cancer progression.
Species:  Human
Source:  Human prostate adenocarcinoma
Components:  200 µg of PC-3 nuclear extract at 6.88 µg/µl.
Extract Composition:  PC-3 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT).
Application Notes:  PC-3 nuclear extract is specifically recommended for studies related to prostate cancer.
Storage:  Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Warning:  For research use only, not for diagnostic or therapeutic use.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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