Cat.No.: | EL-0377 |
Product Name: | K-562 nuclear extract |
Description: | K-562 nuclear extract was prepared from a cell culture of the K-562 human myelogenous leukemia cell line. The K-562 cell line was originally derived from immortalized erythroleukemia cells obtained from a patient with a Philadelphia chromosome-positive chronic myeloid leukemia in blast crisis. These pluripotent cells are widely applicable in research due to their ability to spontaneously differentiate into erythrocyte, granulocyte and monocyte progenitors. K-562 cells are also frequently utilized in in vitro natural killer (NK) cell assays as highly sensitive targets since they lack the expression of MHC class I molecules required for protection against NK activity. |
Species: | Human |
Source: | Human lymphoblast bone marrow; chronic myelogenous leukemia (CML) |
Components: | 200 µg of K-562 nuclear extract at 4.3 µg/µl. |
Extract Composition: | K-562 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT). |
Application Notes: | K-562 nuclear extract is recommended for use in the studies related to 1) differentiation, 2) immunology, and 3) cancer. |
Storage: | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Warning: | For research use only, not for diagnostic or therapeutic use. |
Product Types | ||
◆ Extracts & Lysates | ||
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USA
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