| Cat.No.: | EAb-0183 |
| Product Name: | PKM Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect endogenous levels of Fibronectin 1 in human, mouse and rat samples |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human PKM2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | PKM |
| Purification: | Affinity purification |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Applications: | Immunohistochemistry (IHC),Western Blotting,ELISA |
| Recommended Dilutions/Conditions: |
WB 1:500-1:2000,IHC 1:50-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Rat,Mouse,Human |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P14618 |
| Alternative Name: | pyruvate kinase PKM,Pyruvate kinase,CTHBP, Cytosolic thyroid hormone binding protein, Cytosolic thyroid hormone-binding protein |
| Scientific Background: | This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0054 | PKC Polyclonal Antibody | Inquiry |
| EAb-0183 | PKM Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0078 | Recombinant Human PKN1 Cell Lysate | Inquiry |
| EL-0086 | Recombinant Human PKN2 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0203 | Ro 31-8220 methanesulfonate | Inquiry |
| Related Gene / Proteins | |||
| PKC | PKM | PKM2 | PKN1 |
| PKN2 | |||
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