| Cat.No.: | EAb-0303 |
| Product Name: | MCM6 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human MCM6 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, IHC, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:2000; IHC: 1:100-1:300 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q14566 |
| Alternative Name: | DNA replication licensing factor MCM6,MCG40308,Mcm6,MCM6 minichromosome maintenance deficient 6 (MIS5 homolog,S. pombe),MCM6 minichromosome maintenance deficient 6,MCM6,Minichromosome maintenance complex component 6,Minichromosome maintenance deficient (mis5 S. pombe) 6,Minichromosome maintenance deficient 6 homolog,Minichromosome maintenance protein 6,Mis5,MIS5 homolog,p105MCM |
| Scientific Background: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0011 | Human MCF2L Knockout Cell Line | Inquiry |
| ◆ Antibodies | ||
| EAb-0068 | MCAF Polyclonal Antibody | Inquiry |
| EAb-0303 | MCM6 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0161 | Recombinant Human MCRS1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1225 | Recombinant Human MCRS1, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| MCAF1 | MCF2L | MCM6 | MCM8 |
| MCRS1 | |||
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