MBD3 Polyclonal Antibody


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Cat.No.:  EAb-0669
Product Name:  MBD3 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applications:  WB
Recommended Dilutions/Conditions:  WB; Recommended dilution: WB 1:200 -1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  AI181826 antibody, AU019209 antibody, MBD 3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding protein MBD3 antibody
Scientific Background:  MBD3, or methyl-CpG binding domain protein 3, is a protein that is a member of the methyl-CpG-binding domain (MBD) family, which also includes MeCP2, MBD1, MBD2, MBD4, CLLD8-like, and BAZ2A-like proteins. Although MBD3 is a member of the methyl-CpG-binding domain family, it is not able to bind to methylated DNA. It is a subunit of a multisubunit complex known as NuRD, which is involved in nucleosome remodeling and histone deacetylase functions. It is also thought to mediate the relationship of MTA2, or metastasis-associated protein 2, with the histone deacetylase core complex.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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