| Cat.No.: | EAb-1325 |
| Product Name: | KEAP1 Polyclonal Antibody, Biotin Conjugated |
| Antibody Type: | Polyclonal |
| Conjugate: | Biotin |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19 |
| Scientific Background: | Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0320 | KEAP1 Polyclonal Antibody | Inquiry |
| EAb-0397 | KEAP1 Polyclonal Antibody | Inquiry |
| EAb-1323 | KEAP1 Polyclonal Antibody, HRP Conjugated | Inquiry |
| EAb-1324 | KEAP1 Polyclonal Antibody, FITC Conjugated | Inquiry |
| EAb-1325 | KEAP1 Polyclonal Antibody, Biotin Conjugated | Inquiry |
| Related Gene / Proteins | |||
| KEAP1 | |||
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