| Cat.No.: | EAb-2300 |
| Product Name: | CXXC4 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within the N-terminal region of mouse Cxxc4. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 42 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:1,000 - 1:2,500 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Cxxc4 (CXXC Finger Protein 4) acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 and has been implicated in malignant renal cell carcinoma and colonic villous adenoma. Recently, Cxxc4 has been shown to be involved in the regulation of DNA demethylation. It binds to unmethylated CpGs in DNA and is involved in TET2 downregulation. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0122 | Recombinant Human CXXC1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0942 | Recombinant Human CXXC1, His-tagged | Inquiry |
| PE-0943 | Recombinant Rhesus monkey CXXC1 Protein, His-tagged | Inquiry |
| ◆ Antibodies | ||
| EAb-2300 | CXXC4 Polyclonal Antibody | Inquiry |
| EAb-2301 | CXXC1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| CXXC1 | CXXC4 | ||
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