| Cat.No.: | EAb-2476 |
| Product Name: | p400 Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect p400 |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to a region between C terminal residues 3075 and 3124 of human p400 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | 0.09% Sodium azide, 0.1% BSA, Tris buffered saline |
| Applications: | WB, IP, ChIP, ICC/IF |
| Species Reactivity: | Mouse, Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | CAG repeat protein 32 antibody/CAGH 32 antibody/CAGH32 antibody |
| Scientific Background: | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. |
| Product Types | ||
| ◆ Proteins & Enzymes | ||
| PE-2087 | Recombinant Human p400 protein | Inquiry |
| ◆ Antibodies | ||
| EAb-2476 | p400 Polyclonal Antibody | Inquiry |
| EAb-2731 | p400 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| p400 | |||
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