| Cat.No.: | PE-0588 |
| Product Name: | Recombinant Human TOP2A |
| Product Overview: | Recombinant enzyme overexpressed in a proprietary eukaryotic cell line. |
| Description: | Topoisomerase II is a gene product with conserved catalytic activities and it promotes the progression of DNA damage. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 170 kDa |
| Species: | Human |
| Formulation: | Solution in 10 mM Tris-HCl, pH 7.1, 0.25 M NaCl, 1 mM EDTA, 0.5 mM PMSF, 1 mM 2-mercaptoethanol, 10% glycerol. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TOP2A topoisomerase (DNA) II alpha 170kDa [ Homo sapiens ] |
| Gene ID NCBI: | 7153 |
| Synonyms: | TOP2A; topoisomerase (DNA) II alpha 170kDa; TOP2, topoisomerase (DNA) II alpha (170kD); DNA topoisomerase 2-alpha; DNA gyrase; DNA topoisomerase II, 170 kD; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase II, alpha isozyme; TOP2; TP2A; |
| mRNA Refseq: | NM_001067 |
| Protein Refseq: | NP_001058 |
| MIM: | 126430 |
| Chromosome Location: | 17q21-q22 |
| Function: | ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; chromatin binding; drug binding; enzyme binding; histone deacetylase binding; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase C binding; sequence-specific DNA binding; structure-specific DNA binding; ubiquitin binding; |
| Product Types | ||
| ◆ Proteins & Enzymes | ||
| PE-0587 | Recombinant Human TOP2A, GST-tagged | Inquiry |
| PE-0588 | Recombinant Human TOP2A | Inquiry |
| PE-0589 | Recombinant Human TOP2A, GST-tagged | Inquiry |
| PE-0590 | Recombinant Chicken TOP2A | Inquiry |
| PE-0591 | Recombinant Zebrafish TOP2A | Inquiry |
| Related Gene / Proteins | |||
| TOP2A | TORC2 | TOX1 | TOX3 |
| TOX4 | |||
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