| Cat.No.: | PE-0620 |
| Product Name: | Recombinant Human YY1, FLAG-tagged |
| Description: | YY1 (Yin Yang 1) is a transcription factor that belongs to the GLI-Kruppel class of zinc finger transcription factors and is ubiquitously expressed. YY1 is known to have a fundamental role in normal biologic processes such as embryogenesis, differentiation, replication and cellular proliferation. YY1 exerts its effects on genes involved in these processes via its ability to initiate, activate or repress transcription depending upon the context in which it binds. Since expression and function of YY1 are known to be intimately associated with progression through phases of the cell cycle, the physiologic significance of YY1 activity has been applied to models of tumor biology. It can repress and activate a number of gene promoters and direct histone deacetylases (HDACs) and histone acetyltransferas- es (HATs). YY1 is known to facilitate silencing by the Polycomb protein complex. |
| Applications: | Recombinant YY1 protein is suitable for use in in vitro transcription assays. We recommend to start with a range of protein concentrations (e.g. 5 ng, 50 ng, and 500 ng) to determine the optimal amount needed for each in vitro transcription assay. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~46 kDa |
| Species: | Human |
| Tag: | FLAG |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | YY1 YY1 transcription factor [ Homo sapiens ] |
| Gene ID NCBI: | 7528 |
| Synonyms: | YY1; YY1 transcription factor; DELTA; NF-E1; UCRBP; INO80S; YIN-YANG-1; transcriptional repressor protein YY1; YY-1; Yin and Yang 1 protein; INO80 complex subunit S; delta transcription factor; Yin and yang 1; CF1; NF E1; NFE1; OTTHUMP00000197459; TYY1_HUMAN; UCR motif DNA binding protein; Ying Yang 1; YY 1 |
| mRNA Refseq: | NM_003403 |
| Protein Refseq: | NP_003394 |
| MIM: | 600013 |
| UniProt ID: | P25490 |
| Chromosome Location: | 14q |
| Function: | DNA binding; RNA binding; four-way junction DNA binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; transcription regulatory region DNA binding; zinc ion binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0075 | Recombinant Human YY1 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0618 | Recombinant Human YY1, His-tagged | Inquiry |
| PE-0619 | Recombinant Human YY1 | Inquiry |
| PE-0620 | Recombinant Human YY1, FLAG-tagged | Inquiry |
| PE-0621 | Recombinant Human YY1, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| YY1 | |||
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