Recombinant Human C20orf20 protein


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Cat.No.:  PE-2675
Product Name:  Recombinant Human C20orf20 protein
Background:  Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Applications:  SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  25 kDa including tags
Purity:  > 85 % SDS-PAGE.
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.32% Tris HCl, 0.02% DTT, 20% Glycerol, 1.17% Sodium chloride
Accession#:  Q9NV56
Alternative Names:  C20orf20/Chromosome 20 open reading frame 20/Eaf7
Tag:  His
Amino Acid Sequence:  MGSSHHHHHH SSGLVPRGSH QVPSKVIWDH LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM KEDVDPHNGA DDVFSSSGSL GKASEKSSKD MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG VNRHFHMICI RDKFSQNIGR KEKNSSDLGC KEGADKRKRS RVTDKVLTAN SNPSSPSAAK RRRT
Sequence Similarities:  Belongs to the EAF7 family.
Expression System:  E. coli
Protein Length:  Protein fragment; 1 to 204
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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