| Cat.No.: | PE-1494 |
| Product Name: | Recombinant Human Chromosome 20 0pen Reading Frame 20, His-tagged |
| Product Overview: | Recombinant human C20orf20 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description: | C20orf20 protein, also known as MRGBP, is a 204 amino acid protein which is a part of the NuA4 histone acetyltransferase (HAT) complex that acts to acetylate histone H2A and H4. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. MRGBP has potential to interact with MORF4L1/MRG15 and MORF4L2/MRGX. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 24.5 kDa (224 aa) confirmed by MALDI-TOF |
| Purity: | > 85% by SDS-PAGE |
| Species: | Human |
| Formulation: | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 0.2 M NaCl. |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG VNRHFHMICI RDKFSQNIGR QVPSKVIWDH LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM KEDVDPHNGA DDVFSSSGSL GKASEKSSKD KEKNSSDLGC KEGADKRKRS RVTDKVLTAN SNPSSPSAAK RRRT |
| Expression System: | E. coli |
| Concentrations: | 0.5 mg/ml (determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | C20orf20 chromosome 20 open reading frame 20 [ Homo sapiens ] |
| Gene ID NCBI: | 55257 |
| Official Symbol: | C20orf20 |
| Synonyms: | C20orf20; chromosome 20 open reading frame 20; Eaf7; MRGBP; URCC4; MRG15BP; FLJ10914; MRG-binding protein; OTTHUMP00000031512; MRG (MORF4-related gene)-binding protein |
| mRNA Refseq: | NM_018270 |
| Protein Refseq: | NP_060740 |
| MIM: | 611157 |
| UniProt ID: | Q9NV56 |
| Chromosome Location: | 20q13.33 |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0223 | Recombinant Human C20orf20 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1494 | Recombinant Human Chromosome 20 0pen Reading Frame 20, His-tagged | Inquiry |
| PE-1495 | Recombinant Human C20ORF20, His-tagged | Inquiry |
| PE-1496 | Recombinant Human C20ORF20, His-tagged | Inquiry |
| PE-2675 | Recombinant Human C20orf20 protein | Inquiry |
| Related Gene / Proteins | |||
| C20orf20 | |||
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