| Cat.No.: | PE-0716 |
| Product Name: | Recombinant Human GMNN, GST-tagged |
| Product Overview: | Recombinant Human GMNN protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
| Description: | This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Tag: | GST |
| Expression System: | E. coli |
| Protein Length: | 1-209a.a. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | GMNN geminin, DNA replication inhibitor [ Homo sapiens ] |
| Gene ID NCBI: | 51053 |
| Synonyms: | GMNN; geminin, DNA replication inhibitor; geminin; Gem; |
| mRNA Refseq: | NM_001251989 |
| Protein Refseq: | NP_001238918 |
| MIM: | 602842 |
| UniProt ID: | O75496 |
| Chromosome Location: | 6p21.32 |
| Function: | histone deacetylase binding; protein binding; repressing transcription factor binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0088 | Recombinant Human GMNN 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0713 | Recombinant Human Geminin, DNA Replication Inhibitor, His-tagged | Inquiry |
| PE-0714 | Recombinant Human GMNN protein, His-tagged | Inquiry |
| PE-0715 | Recombinant Human GMNN, His-tagged | Inquiry |
| PE-0716 | Recombinant Human GMNN, GST-tagged | Inquiry |
| Related Gene / Proteins | |||
| GMNN | |||
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