AMC
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DYE-154 | AMC [7-Amino-4-methylcoumarin] | N/A |
|
AMC involved in several pathways and played different roles in them. We selected most pathways AMC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
AMC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AMC itself. We selected most functions AMC had, and list some proteins which have the same functions with AMC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
AMC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMC here. Most of them are supplied by our site. Hope this information will be useful for your research of AMC.
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Q&As (10)
Ask a questionAlterations in AMC expression levels or mutations can impact cellular apoptosis sensitivity and resistance, influencing the susceptibility of cells to apoptotic stimuli.
AMC promotes the permeabilization of the mitochondrial outer membrane, leading to the release of pro-apoptotic factors, such as cytochrome c, into the cytoplasm.
The interaction between AMC and other cellular processes, such as autophagy or cell cycle progression, can influence apoptotic outcomes by crosstalk mechanisms and molecular signaling networks.
AMC interacts with Bcl-2 family proteins, such as Bax and Bak, to regulate mitochondrial outer membrane permeabilization and initiate apoptotic signaling.
Post-translational modifications, including phosphorylation and proteolytic cleavage, regulate the activity and stability of AMC, modulating its involvement in mitochondrial apoptosis.
AMC exhibits a primarily mitochondrial localization, although it may translocate to the cytoplasm and other subcellular compartments under specific conditions.
AMC is a crucial component of the apoptosome, which forms upon cytochrome c release and activates caspase cascades, ultimately leading to apoptosis.
AMC expression and activation are regulated in response to cellular stress or apoptotic stimuli through complex mechanisms involving transcriptional regulation, post-translational modifications, and protein-protein interactions.
AMC plays a role in regulating mitochondrial dynamics by participating in fission-fusion processes and influencing the balance between mitochondrial fusion and fission events.
AMC contributes to mitochondrial quality control mechanisms by participating in mitophagy, the selective clearance of damaged mitochondria, and influencing mitochondrial biogenesis processes.
Customer Reviews (3)
Write a reviewCompatible with multiple protein detection platforms.
Comprehensive analysis of protein-protein interaction networks.
Enhanced assay sensitivity for detection of low-abundance proteins.
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